This is a fantastic example of materials innovation by Queen’s University Belfast in the growing area of drug-device combination products, moving beyond just the drug component by adding some stimulus-sensitive property to allow the catheter to respond to a potential infection. Watch this space to keep up with any further developments in this area. Chris Penfold

A polymer that combines drug-eluting and self-cleansing agents could reduce the risk of bacterial infection through urinary catheters, say researchers at the University.

The material, derived from esters of acrylic and methacrylic acid, is melt-extruded in a confidential multilayer extrusion mechanism to produce a catheter surface that continuously delivers antimicrobial agents over prolonged periods, minimising bacterial colonisation.

‘Although medical device technology has made significant advancements, the inherent problems associated with implanted urinary devices and the significant role microbial biofilms play in device-related infection are now widely recognised as major disadvantages of an otherwise highly effective treatment strategy’, says Dr Gavin Andrews, who is leading the project at the University’s School of Pharmacy.

Via Materials World Magazine, 01 Jan 2010

Click on the following link to read the full article Self-cleansing medical devices