This limited edition Coco Cola design makes great use of their brand colours, very clean and unfussy.  Shame it’s only going to be available in the US.  Wonder what we will get in the UK for the summer Olympics.

Coca-Cola has released special-edition packaging for the US market to celebrate the Vancouver Winter Olympic Games that start tomorrow.  For the full story visit packagingnews.co.uk

popeye spinach packaging polymers?

‘Vegetarian’ polymers seem to be on the increase with yet another innovative initiative that, this time, uses natural cress plant waste, which is combined with a variety of different polypropylene grades to produce a range of packaging materials to suit different types of products with a variety of finishes. Allegedly they are produced using significantly lower CO² emissions than ‘conventional’ plastics.

The material called ‘Agriplast’ has been developed by German bio manufacturing company Biowert, which sources the cress-based waste from farms in the immediate area around Brensbach, in southern Germany, where the factory is based.

This sounds like a really innovative initiative and the the project is a collaboration between German company AHA Kunstofftechnik and French-based packaging manufacturer Cosmeco, who have combined resources to develop this material for use, initially, in cosmetics packaging.

Rumour has it that use of spinach for this type of polymer project could be a next-step development, something that could potentially really increase material tensile properties and produce a product as strong as iron – but this has yet to be verified and Mr P.Peye was unavailable for comment LOL

The full ‘Agriplast’ natural cress article, 8th Feb 2010, can be read here at www.cosmeticsdesign.com

Thanks to @MarktheSpaMan for bringing our attention to this article via Twitter

A recent Los Angeles Times article examines how an increase in counterfeit condoms in China has health officials fearing the worst — the products “may in fact spread infectious diseases, tarnishing the axiom that condoms mean safe sex.”

The newspaper continues, “Authorities estimate that up to a third of the contraceptives used in some parts of China are counterfeits, despite improvements in state food and drug oversight. None of the counterfeits are properly sterilized, and others are of such inferior quality that they could rupture during use.”

The article details how authorities are attempting to track down what they estimate are more than one million condoms distributed throughout China, and notes how the knock-off condoms were uncovered in discount stores in New York, Texas and Virginia in 2008.

Thanks to @TheBodyGlobal for bringing our attention to this article via Twitter. More articles like this can be read at: www.thebody.com

This is a fantastic example of materials innovation by Queen’s University Belfast in the growing area of drug-device combination products, moving beyond just the drug component by adding some stimulus-sensitive property to allow the catheter to respond to a potential infection. Watch this space to keep up with any further developments in this area. Chris Penfold

A polymer that combines drug-eluting and self-cleansing agents could reduce the risk of bacterial infection through urinary catheters, say researchers at the University.

The material, derived from esters of acrylic and methacrylic acid, is melt-extruded in a confidential multilayer extrusion mechanism to produce a catheter surface that continuously delivers antimicrobial agents over prolonged periods, minimising bacterial colonisation.

‘Although medical device technology has made significant advancements, the inherent problems associated with implanted urinary devices and the significant role microbial biofilms play in device-related infection are now widely recognised as major disadvantages of an otherwise highly effective treatment strategy’, says Dr Gavin Andrews, who is leading the project at the University’s School of Pharmacy.

Via Materials World Magazine, 01 Jan 2010

Click on the following link to read the full article Self-cleansing medical devices

Drug approvals from the Food and Drug Administration were flat last year compared with 2008 and warnings fell, even as the agency’s new leadership struck a tougher stance on safety.

The FDA approved 26 first-of-a-kind prescription drugs last year, up slightly from 25 in 2008, according to figures from Washington Analysis, an investment research group. New drugs cleared in 2009 included Novartis’ kidney cancer drug Afinitor and Bausch and Lomb’s pink eye medicine Besivance.

Chris Penfold – there are a number of reasons froi this trend, one of them being a reduced number odf applications – so we can’t read too much in to this report.

Sourced from Pharmaceutical & Medical News, 6th January 2010 – Washington, USA

Read the full article at: Pharmaceutical & Medical Packaging News

Below is a really interesting technological packaging advancement that is truly exciting and could have major benefits in the healthcare and pharma packaging & clinical trials sectors. Design Cognition also believe that this technology has further application in other dosage forms and sectors and is working with DSM TCG & GP Solutions (UK) Ltd to develop the OtCM™ and Dose Guard™ technologies in innovative ways to meet the demands of end-users and industry and bring this product to market in a viable & cost-effective manner.

Please contact me (chris@designcognition.com) if you’d like more information or come and visit us at Packaging Innovations at the NEC, Birmingham UK on 24th or 25th Feb (stand 582), where we can discuss in more detail. You can register HERE.  Chris Penfold

When was the last time you forgot to take your medication? Odds are that it was within the last week. This makes you part of the millions of patients who don’t take their medications as prescribed by their physician. Medication non-adherence, or mal-compliance, as it is commonly called, is a problem that disrupts the healthcare system in many ways. If you don’t take your medication odds are that you won’t get the full benefit of the treatment. As former US surgeon general Dr. C. Everett Koop said, “Drugs don’t work in people who don’t take them”. In the worst case, you could be among the patient population who are hospitalized as a result medication non-adherence. The cost to the healthcare system? Phenomenal! Mortality count? Sinister! Morbidity rates? Unacceptable!

At its root, this problem, like many, is a problem of human behaviour. Even Hippocrates (460-377 BC), the “Godfather of Medicine”, gave early warnings of the non-compliance issues to his students and colleagues. (”Keep watch for that fault in patients which makes them lie about the taking of things prescribed.”). Even though we are “creatures of habit”, we often lose momentum when taking medications, especially for chronic conditions.

The Non-Compliance Money Waste List

There have been several attempts at using technology to influence compliance rates. As one scans the Web looking for potential help, some solutions that arise include:   (1) A variety of medication reminders that will beep, blip or blurt when it is time to take your medication. (2) A variety of devices that can track the number of times a medication dosage has been removed from a medication pack or a medication container (USA) that has been opened. The data collected can be downloaded at the doctor’s office or pharmacy to check compliance statistics. (3) A variety of devices that can remind the patient to take their medications and confirm that they have taken it by pressing a button to send the data.  (4) A miscellaneous group of reminder devices with alarms, like automated pill boxes or wrist watches.

OtCM™ -  Objective therapy Compliance Measurement.

One of the weaknesses of these approaches is that one can never guarantee that the patients have taken their medicine after an alarm. In fact, one can’t detect if the medication unit dosage has been taken, or if the medication unit dosage has even been taken at the right time.

A new technology has arrived that has the potential to dramatically impact the therapy compliance rates for individuals, particularly seniors, as they go about their daily lives. The name of this technology is OtCM™, Objective therapy Compliance Measurement, using the most recent RFID/NFC (Radio Frequency Identification, Near Field Communication) technology, including embedded sensor functionalities, and combined with printed organic electronics.  The OtCM™ application was invented by Jos Geboers and Willem Kort, who are working in the healthcare industry, especially in clinical pharmaceutical R&D, Health Economics, Outcomes Research and Patient Recorded Outcomes.  To that purpose Messrs. Geboers and Kort initiated the foundation of a consortium that includes all players, i.e. top listed pharmaceutical companies, medication packagers, health insurers and Royal DSM N.V.: “The Compliers Group” (DSM TCG).  DSM TCG wanted a way to be as certain as possible that patients were taking their medications at the correct frequency each day. They knew that, whatever solution they decided on, it needed to be “real time” since any delays in therapy could have serious health consequences. A novel system for measuring the time and quantity of drugs taken out of conventional, existing medication packaging or medication container, is used.  “Leading” versus “Bleeding” edge …

The existing medication package will do …

The system consists of conventional, existing medication blister pack (or “bottle”) of a given prescription drug furnished with “organic electronics” (circuitry, power supply), i.e. functional polymers and coatings, to print “the micromechatronic blister/bottle”. A “traditional” silicon RFID/NFC IC (Integrated Circuit) that has been especially designed for OtCM™ with integrated interfaces for i.e. clock and temperature functionality, provide the intelligence to identify data (date-time) of pills/capsules that have been taken out of the blister pack/bottle, whilst wireless Radio Frequency (RF) techniques (NFC, Near Field Communication) are able to transfer data wirelessly from the “OtCM™ enabled blister/bottle” onto DSM TCG’s webserver.

Driven by the intelligence of the RFID chip, embedded in the “mechatronic circuitry”, and the printed power supply (capacitator, battery), an electric current is circulating through the circuitry of the packaging at regular time intervals. As soon as a dosage is removed out of the packaging, the chip is activated. This information is stored. When in close proximity of a (NFC) reader,  the recorded information in the packaging will be transferred and stored in the server to populate the Therapy Compliance Database of active patients, under all regulatory recommended & required security and privacy conditions, locally and globally.

The standard existing medication blister package will do at a fraction of the traditional costs!

The concept of using the technology of printing functional polymers and coatings is an innovative approach. A large variety of  applications in real-life situations has been brought about, especially for purposes of identification of products and, consequently, the packaging of products.  The standard medication blister package will do at a fraction of the traditional costs!   Moreover, until now, traditionally available therapy compliance devices are extremely costly, even if mass-produced. Mass produced RFID-tags combined with polymer printing will introduce low-pricing schedules, based on factors of 90-95% reduction vs. currently available “traditional electronic” OCM devices, i.e. pill boxes or so-called “smart pill boxes”.

DSM TCG’s OtCM™ technology can be combined with GP Solutions (UK) Ltd’s patented and approved Dose Guard™ solution; a child resistant senior friendly secondary barrier that when applied to a blister pack will render it safe for use. Both “come with the standard, existing medication package”.  From surveys it has been identified that patients and health practitioners (physicians, medical specialists, pharmacists) only appreciate the enabling of OtCM™ right from the medication packaging. There obviously is no need for an additional, “stand-alone” therapy compliance measurement (recording) device separated from the medication package.

During OtCM™ we measure through the standard medication packaging:

(1) when the pill/capsule is taken,

(2) the location of the removed pill/capsule onto the blister packaging,

(3) the correct dosing schedule,

(4) an acoustic signal might prompt the for action,  data re: expiration date,

(5) production information re: temperature, batch IDs from the production line,  drug interaction alerts.

This real-time “interventional approach” is what stands apart from other compliance solutions.  In conclusion, it is clear that there are several technological approaches that are aimed squarely at the problem of medication compliance. Though these advances give our “inner geek” some encouragement, they are ultimately targeted at making sure that at-risk populations stay on track as they take medications to improve their health status. David Rosa, Willem Kort

You can find further information on compliance and evolving technologies, via Design Cognition’s sister site ‘The Pharma Gateway‘. Also, if you are interested in our forthcoming compliance workshops – let us know.

Contact Chris Penfold (chris@designcognition.com).

The use of Multisensoric for confectionery packaging on the increase

By Jane Byrne , 15-Dec-2009

Appealing to consumers’ five senses through innovative packaging techniques can result in increased brand loyalty and greater impact at point of sale, and it is a key driver in confectionery packaging, according to the organisers of the 2010 Pro Sweets trade show.

Multisensoric is an approach to packaging design that allows packaging to stimulate and arouse emotions in consumers to encourage purchase and examples include such elements as striking colour schemes, windows to view the product, exciting rustling sounds and foldout trays.

The Pro Sweets team said that, as a result, the confectionery industry is increasingly focused on touch, sight and sound finished packaging elements such as foil lamination, textured embossing, and varnishes.

via Multisensoric trend key to confectionery packaging, claims German group.

The dangers of counterfeiting drive the need for package and brand security. The following is an extract from a recent Converting Magazine event in the US, detailed by Natalie Hasselbacher, Converting Magazine, 3rd June 2009, which provides some useful insights into successful anti-counterfeiting and security techniques and technologies.

Three speakers presented during an anti-counterfeiting session on the importance of product security and possible ways for its implementation among capable converting facilities. Discussions highlighted a desperate need for package security to save a company’s brand whilst also ensuring safety to consumers.

Jim Reiman, Sales Director at Sun Chemical Security, said once anti-counterfeiting technology is applied to a package or label, the most important thing for brand owners to consider is a strategy and who will authenticate. “Articulating a high-level strategy and defining the problem is important,” he said. “Clearly articulating requirements with metrics and an internal agreement among company employees for proper implementation is a must. You have to question whether consumers, customs, investigators or retail will authenticate.”

Reiman also discussed Sun Chemical’s newest technologies that reportedly fight counterfeiting. The Verigard is a low level taggant that is said to work in any ink or adhesive while printing using most methods including flexo, gravure and offset.

A second speaker, Jim Colby, a Consultant for ExPev Solutions, referred to interdiction, authentication and a secure supply chain as the three ways to stop counterfeiting.

Thirdly, Juliet Midlik, Sales Manager for Prime UV Systems, mentioned that most of the company’s customers purchasing UV drying systems are applying anti-counterfeiting coatings and inks on food packaging.

The full article can be read here: http://tinyurl.com/yaq3nf4

You can find further information on counterfeiting and evolving technologies, via Design Cognition’s sister site ‘The Pharma Gateway‘. Also, if you are interested in our forthcoming counterfeiting workshops – let us know.

Interesting article and data  on the importance of continued investment into innovative packaging and graphics (Annie)

Year long survey consistently finds that structure might best communicate innovation, especially with supportive graphics. Materials and production also are good barometers. In any economic environment, innovation is key to growth. But, during a recession, many companies are tempted to reduce spending on innovation to save money. Luckily, this is not an absolute rule. Daring brands still pushed the boundaries of packaging innovation in 2009.Earlier this year, Shelf Impact! and international brand consultancy Dragon Rouge formed a partnership to ask branding and packaging professionals to evaluate recent product and packaging innovations. Each quarter, we asked a sample of hundreds of Shelf Impact! readers, from brand managers to designers to materials suppliers, to rate a selection of packages on matters of innovation. View an image and brief description of each of the 10 packages reviewed this quarter.

via Shelf Impact: “Achieving attention-getting innovation” Filed In:.

NOTTINGHAM science companies will lead a delegation of UK firms pitching for business during one of the biggest events in the American pharmaceutical industry’s calendar.

Businesses from the city account for one-third of the firms in the English delegation attending a reception during the American Association of Pharmaceutical Sciences (AAPS) annual meeting in Los Angeles.

They will meet potential customers and investors next week at an event hosted on their behalf by the British Consul in LA, Dame Barbara Hey.

The Nottingham firms taking part in the 20-strong delegation are Critical Pharmaceuticals, Design Cognition, Food and Drug Analytical Services, Molecular Profiles, Pharmaceutical Development Services and R5 Pharmaceuticals.

The US pharmaceutical market is the biggest and most lucrative in the world, with companies bidding for work in a field where the biggest firms routinely outsource research, development and service work to smaller companies.

Some of the Nottingham firms will be going to link-up with existing contacts, while others, such as specialist packaging and product development firm Design Cognition, are first- timers. Chris Penfold, the company’s chief executive, said: “We are on a fact-finding mission, to learn as much as possible about the US market and assessing where and how we can add value for US pharmaceutical companies looking to export, through our understanding of packaging requirements and regulations of global markets.”

His company is working closely with Pharmaceutical Development Services, which already has an office in the US state of South Carolina, another industry hotspot.

“Making a move into the US requires a great deal of market as well as regulatory intelligence,” said managing director Michael Gamlen.

“Close working relationships and collaboration are key to success and our respective consultancy services dovetail perfectly to add potential value for US companies.”

To read the full article, click here: http://bit.ly/Ox0hr

Watch this space for further information as I will be following up with This is Business- East Midlands (Nottingam Evening Post) after the AAPS event.